Tag Archives: science & technology

Brushing teeth prevents preterm birth

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Preterm births are easier prevented than thought. Researchers in the United States have found that brushing your teeth properly and maintaining proper oral hygiene reduces the chance of early labour by a large extent.

Researchers from Case Western Reserve and Yale Universities Previously undiscovered bacteria usually found in the mouth could be responsible for up to 80% of early preterm labours.

The research could help doctors prevent preterm births by encouraging oral hygiene or stop early labour from developing by prescribing targeted antibiotics, Discovery News reported on its website on Wednesday.

“The earlier the woman goes into preterm labor, the higher the chance that she will be infected,” said Yiping Han, a doctor at Case Western University and the first author on the study.

Most human pregnancies last about 40 weeks. A birth prior to 37 weeks is classified as preterm. Babies born preterm can face many hurdles: vision and hearing loss, cerebral palsy, mental retardation, even death.

Labour itself is still somewhat of a mystery to science, which makes puzzling out preterm labour even more difficult. Anything from socioeconomic status and race to bacterial infection and genetics has been linked to preterm births, but a definitive cause is still elusive.

Han and her colleagues think they have found a major cause, at least in mice. By infecting the rodents with Bergeyella, previously unknown bacteria found in the mice, the researchers caused preterm births.

In humans, the scientists showed a strong correlation between infection and preterm births. Doctors removed amniotic fluid from 46 different women with potentially higher risk pregnancies. Of that group, 21 delivered an early preterm baby (32 weeks or earlier). Nineteen of those women, or about 85%, were positive for previously undetected bacteria.

The bacteria normally live in the mouth, but if a cut, cavity or other wound allows the bacteria to enter the blood stream, they can travel and eventually colonize the uterus. That triggers an immune response, which can inflame the uterus and eventually cause a mother to go into labour prematurely.

To identify bacteria behind preterm labour, doctors used polymerase chain reaction (PCR). Using PCR, the scientists identified the Bergeyella bacterium, as well as DNA belonging to 10 or 11 different strains of newly identified bacteria. Now that doctors know about another link to preterm labour, the next step is to treat it. Antibiotics that specifically target these new bacteria are currently being tested.

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A pill ‘to curb smoking damage’ soon

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Finding it hard to quit fags? Fret not, for researchers are close to developing a pill which they claim could mitigate some of the negative health effects of smoking.

According to a report in the ‘New Scientist’, a team at Boston University School of Medicine has already identified 28 molecules known as microRNAs, that are produced in abnormal amounts in cells lining the airways of smokers.

And, if the levels of these molecules could be restored to that of non-smokers it might allow chronic smokers to improve their health prospects as well as enable people to puff without any significant damage to their health.

“These microRNAs serve to regulate the gene expression changes occurring in people who smoke and who get smoking rel- ated diseases, including cancer,” lead researcher Avrum Spira was quoted as saying.

In fact, in their study involving ten smokers and ten non-smokers, the researchers have found one of the microRNAs, called mir-218, controls a group of genes that usually protect lung and airway cells from oxidative damage caused by smoke.

“We think the level of activity of mir-218 is crucial in how a smoker defends his or herself against any injury and potential development of lung disease,” Spira said.

And, giving supplements of mir-218 to smokers, or developing a drug that restores levels of disrupted microRNAs to normal could help mitigate some of the damaging effects of smoking, the researchers believe.

“We might be able to alter the host’s response to tobacco smoke so that it is a protective one,” Spira said.

The findings of the study have been published in the latest edition of the ‘Proceedings of the National Academy of Science’ journal.

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Vicks VapoRub can harm children under 2

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Vicks VapoRub, a common cold remedy, can cause respiratory distress in children under 2 when inappropriately applied directly under the nose, US researchers said on Tuesday.

They said using the Procter & Gamble Co product in this way can cause a young child’s tiny airways to swell and fill with mucus, triggering severe breathing problems.

“The only problem we’ve seen is in a small child when it has been put under the nose,” Dr. Bruce Rubin of Wake Forest University School of Medicine in North Carolina, said in a telephone interview.

Rubin said the ingredients in Vicks can be irritants, causing the body to produce more mucus to protect the airway. And since infants and young children have airways that are much narrower than those of an adult, any increase in mucus or swelling can narrow them severely.

“The company is really clear it should never go under the nose or in the nose for anybody and it shouldn’t be used in children under 2,” said Rubin, whose study appears in the journal Chest.

While the researchers only tested the Vicks product, Rubin said similar products, including generic versions, could cause the same negative effects in infants and toddlers.

Rubin and his colleagues began looking at use of the medication after treating an 18-month-old girl who developed respiratory distress after the salve was put under her nose.

They studied ferrets, which have an airway anatomy similar to humans. In the animals with a chest infection, the product increased mucus secretion and decreased the animal’s ability to clear mucus.

“We were able to document changes that we think explain this,” Rubin said.

David Bernens, a spokesman for P&G, said the finding came as a surprise. “Vicks VapoRub has been proven safe and effective through multiple clinical trials. It has been in the market for over 100 years,” Bernens said, noting that the label says the product should not be used in children under age 2 without a doctor’s advice, and not under the nose.

“We warn people not to do that,” he said.

Since the initial episode, emergency doctors at the medical center have begun asking all parents of children in respiratory distress if they used the Vicks product in a similar way and they have seen two more cases, Rubin said.

“I recommend never putting Vicks in, or under, the nose of anybody — adult or child,” Rubin said in a statement, adding that he would never use it in a child under age 2.

Dr. James Mathers, president of the American College of Chest Physicians, said in a statement that parents should consult their doctor before giving any over-the-counter medication to infants and young children, particularly cough and cold medications, which can be harmful.

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Dead woman gives birth

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A British woman gave birth to a baby by caesarean section two days after she had collapsed and died from a brain haemorrhage, it was reported yesterday.

The Guardian website, www.guardian. co.uk, reported that former British champion ice skater Jayne Soliman, 41, was declared brain-dead at an Oxford hospital but doctors managed to keep her heart beating long enough to deliver Aya Jayne by caesarean section.

Soliman was only 25 weeks’ pregnant when she collapsed at home last Wednesday, having complained of a headache.

The website reported: “Doctors said the skater had suffered a brain haemorrhage caused by an aggressive tumour which had struck a major blood vessel.

“She was given large doses of steroids to help the child’s lungs develop and within 48 hours gave birth to the baby, who weighed 0.95kg. Her husband, Mahmoud, was with her when the child was born.”

Doctors briefly put the baby next to Soliman before they turned off the life- support system, the Guardian said

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Contamination fears over two-headed Australian fish

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Toxic chemical contamination was the likely cause of fatal fish mutations in northern Australia in which thousands of bass larvae spawned with two heads, an expert said Wednesday.

Matt Landos, an aquatic animal specialist and member of the Australian College of Veterinarian Scientists, said the mutant larvae at a Noosa River fish farm survived just 48 hours and were dying en masse.

“When we used the water on-site or have taken bass from the Noosa River those fish appear to have been contaminated and they give rise to deformed or convulsing larvae,” he told AFP.

“I have been working in aquaculture for 10 years and this is the first time I have ever seen anything like it.”

Tests had excluded the presence of a virus or bacteria, leading Landos to suspect that pesticides from a neighbouring macadamia nut farm were to blame.

“It leaves us sitting with toxic chemical contamination as a likely cause,” he said. “I believe that it’s some of these chemicals at very low levels that are impacting on the breeding ability of these fish.”

Deformities in the fish had increased as the neighbouring macadamia nut plantation had expanded in the past two years to virtually border the hatchery on three sides, said Landos.

Rapidly developing pest-control technology also meant smaller particles of pesticide could travel further.

Chickens, horses and sheep at the hatchery were also experiencing birth defects and foetal deaths at abnormally high rates, he said.

The organophosphates in question — carbendazim and endosulfan — had been recognised as potentially dangerous and even banned in some countries, but were still recommended for use in Australia, said Landos.

The Queensland state government said tests gave no indication that the macadamia farm was using the chemicals against the manufacturers’ instructions.

The local fisheries department is investigating, and expects to receive results from tests of dead fish specimens next month.

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Scant evidence herbal remedies ease menopause: study

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There is little or no evidence to back claims that herbal treatments can alleviate the symptoms of menopause, according to a medical review published on Wednesday.

The paper appears in the Drug and Therapeutics Bulletin, published by the British Medical Association (BMA).

It looks at clinical studies into plants whose extracts are becoming increasingly popular among women eager to ease mood swings, tiredness, hot flushes, loss of libido and other outcomes of the hormone changes that occur at menopause.

The main herbs are black cohosh (Actaea racemosa); red clover (Trifolium pratense); dong quai, also spelt as dong gui (Angelica sinensis); evening primrose (Oenothera biennis) and ginseng (Panax ginseng).

The authors say much research falls short of scientific criteria when it comes to assessing these herbs for effectiveness and safety.

For instance, the number of participants in many studies is too small, and the duration of the trial is too short to get a definitive answer.

Of those trials deemed acceptable, the evidence is equivocal for black cohosh, they say. Some trials suggest the herb is beneficial, while others suggest it is not.

Watchdogs in Britain have given “traditional herbal registration” to a product containing black cohosh as a menopausal treatment, but have also said women who take the plant should be warned of its potential toxicity for the liver.

“There is no convincing evidence that red clover extracts have a beneficial effect (and) there is little evidence for or against benefit with other herbs commonly used for menopausal symptoms, such as gong quai, evening primrose oil, ginseng, wild yam, chaste tree, hops and sage,” the paper adds.

The review notes that herbal products can be easily purchased at shops or over the Internet and are often assumed to be “safe” on the grounds that they are “natural.”

“In reality, herbal medicines have pharmacological actions, and so can cause unwanted effects and have potentially dangerous interactions with other medicines,” both herbal and conventional, it warns.

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Is it a bird? Is it a plane? No, it’s skycar

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A British adventurer plans to set off Wednesday in a home-made vehicle which can transform itself from a car into an aircraft in minutes destination Timbuktu.

On the ground the Skycar runs on a biofuel-powered engine, and can accelerate from zero to 100 kilometres (60 miles) per hour in 4.5 seconds.

But with a powerful fan on the rear its take-off speed is 60 kph (37 mph), and once in the air it can fly at speeds of up to around 110 kph (70 mph), cruising at 2-3,000 feet with a paraglider-style canopy holding it aloft.

At 9:00 am (0900 GMT) Wednesday, inventor Giles Cardozo will leave the British capital for the 6,000-km (3,750-mile) trip through France, Spain and

north Africa, across the Sahara to the fabled desert city of Timbuktu in Mali.

The journey is expected to take some 40 days, during which they plan to soar over the Pyrenees, and the Straits of Gibraltar between southern Spain and Africa.

With four-wheel drive it can allegedly deal with the most rugged terrain, starting on the city streets of London and ending in the sands of the Sahara.

“It’s not like a car — it’s more like a dune buggy,” said Cardozo. “But no other dune buggy or car has flown like this thing before. It flies brilliantly.

“It flies at about 70 mph (110 kph) and drives at 120 mph (193 kph), so it’s a really cool bit of kit,” added the 29-year-old, whose trip is backed by famous British explorer Ranulph Fiennes as patron.

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A supercar that runs on wind energy

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Get ready for a supercar that could reach a top speed of 155mph without harming the environment, for it runs on wind energy.

Designed in California, the environmentally friendly Formula AE car will initially use a solar-powered battery to move, but later depend upon the airflow around it to power a turbine.

The high performance car will take less than four seconds to accelerate from 0 to 60 mph.

The car is expected to cost around 100,000 pounds when it hits the market.

The two-seater’s bodywork boasts paper-thin solar panelling that could fully charge the battery in just 1.5 hours.

However, this time will be reduced to just six minutes with a new prototype battery.

A full battery would enable the drivers to cover more than 200 miles or to race around a track for at least an hour.

An advanced alternating current induction motor with a power output of 212 kilowatts will propel the Formula AE.

In fact, the chassis will be constructed from lightweight aluminium and super strong steel in a Formula 1-style monocoque shell. Rory Handel and Maxx Bricklinas from Beverly Hills, California designed the sleek motor of the car, and they expect the prototype to be completed in August.

“The Formula AE car embraces a rarely thought of alternative source of energy,” the Telegraph quoted a RORMaxx spokesman as saying.

He said: “The target market would be the sports car, track day, eco-concerned auto-enthusiast. In addition, those enthusiasts who support and would want to promote the future development of revolutionary green technologies.”

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Experts plead to save tropical forests in peril

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:US experts on Monday pleaded for boosted efforts to protect tropical forests, which are key to ensuring biodiversity and fighting climate change but are increasingly threatened by deforestation.

“I am gravely concerned about what is happening with tropical forests,” William Laurance, a researcher with the Smithsonian Tropical Research Institute in Panama told AFP.

“There is a very high rate of destruction of the old growth, ancient forests.”

He said the equivalent of 50 football pitches of virgin rainforest was being destroyed every minute amid global warming, large scale habitat fragmentation, and changes in rainfall.

Intense hunting in areas of the tropics was also leading to the disappearance of “hundreds of species of amphibians,” he said.

“Now we have synergy among those different threats,” Laurance said.

“So when you talk about global warming for example because it’s getting hotter, species in the tropics, where it’s possible, will naturally try to move up to higher elevations where it’s a little bit cooler.

“In many cases they will be trapped by habitat construction, cattle pass, degraded lands,” he warned.

Laurance is one of the authors of a report presented Monday to a conference organized in Washington by the Smithsonian Natural History museum.

“Indonesia is now in terrible shape, losing more than two million hectares (4.9 million acres) of forest per year. Borneo is being devastated,” he said.

More than half of the planet’s 20 million square kilometers (eight million square miles) of rainforests has already been cleared for human use, while another five million square kilometers (two million square miles) has been selectively logged, said Greg Asner from the Carnegie Institution.

But he said major swathes of land, or some 350,000 square kilometers (140,000 square miles), have been abandoned by human inhabitants and are beginning to grow back.

“Moreover, the regrowth is relatively quick. The forest canopy closes after just 15 years. After 20 years, about half of the original biomass weight has grown back,” he said.

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Open-plan office workers sick and stressed: study

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Open-plan offices are making people sick, with workers more likely to suffer stress, catch a cold and be less productive, Australian researchers have found.

A review of global studies into the impact of modern office design found the switch to open-plan spaces had been overwhelmingly negative, with 90 percent reporting adverse health and psychological effects.

High levels of stress and conflict, elevated blood pressure, and rapid staff turnover were associated with open-plan environments, according to review author Vinesh Oommen.

“Employees face a multitude of problems such as the loss of privacy, loss of identity, low work productivity, various health issues, overstimulation and low job satisfaction when working in an open plan work environment,” Oommen wrote in the latest Asia-Pacific Journal of Health Management.

Workers were plagued by insecurity, he said, ever-conscious of their colleagues’ ability to see what they were doing on the computer and eavesdrop on their phone calls.

High noise levels led to impaired concentration and low productivity, he said. There was a higher incidence of workplace conflict, with people sitting so close to their neighbour that even a ringing phone could irritate.

Ease of germ transmission also meant illnesses such as influenza were more swiftly passed around.

“It is estimated that organisations can save up to 20 percent in development costs when creating an open plan work environment,” Oommen wrote.

“(But) workplace design must go beyond cost-saving to cater for the multifaceted social and psychological needs of employees.”

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